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Expert Syst Appl ; 229: 120477, 2023 Nov 01.
Article in English | MEDLINE | ID: covidwho-2316031

ABSTRACT

In December 2019, the global pandemic COVID-19 in Wuhan, China, affected human life and the worldwide economy. Therefore, an efficient diagnostic system is required to control its spread. However, the automatic diagnostic system poses challenges with a limited amount of labeled data, minor contrast variation, and high structural similarity between infection and background. In this regard, a new two-phase deep convolutional neural network (CNN) based diagnostic system is proposed to detect minute irregularities and analyze COVID-19 infection. In the first phase, a novel SB-STM-BRNet CNN is developed, incorporating a new channel Squeezed and Boosted (SB) and dilated convolutional-based Split-Transform-Merge (STM) block to detect COVID-19 infected lung CT images. The new STM blocks performed multi-path region-smoothing and boundary operations, which helped to learn minor contrast variation and global COVID-19 specific patterns. Furthermore, the diverse boosted channels are achieved using the SB and Transfer Learning concepts in STM blocks to learn texture variation between COVID-19-specific and healthy images. In the second phase, COVID-19 infected images are provided to the novel COVID-CB-RESeg segmentation CNN to identify and analyze COVID-19 infectious regions. The proposed COVID-CB-RESeg methodically employed region-homogeneity and heterogeneity operations in each encoder-decoder block and boosted-decoder using auxiliary channels to simultaneously learn the low illumination and boundaries of the COVID-19 infected region. The proposed diagnostic system yields good performance in terms of accuracy: 98.21 %, F-score: 98.24%, Dice Similarity: 96.40 %, and IOU: 98.85 % for the COVID-19 infected region. The proposed diagnostic system would reduce the burden and strengthen the radiologist's decision for a fast and accurate COVID-19 diagnosis.

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Diagnostics (Basel) ; 12(2)2022 Jan 21.
Article in English | MEDLINE | ID: covidwho-1648775

ABSTRACT

COVID-19 is a respiratory illness that has affected a large population worldwide and continues to have devastating consequences. It is imperative to detect COVID-19 at the earliest opportunity to limit the span of infection. In this work, we developed a new CNN architecture STM-RENet to interpret the radiographic patterns from X-ray images. The proposed STM-RENet is a block-based CNN that employs the idea of split-transform-merge in a new way. In this regard, we have proposed a new convolutional block STM that implements the region and edge-based operations separately, as well as jointly. The systematic use of region and edge implementations in combination with convolutional operations helps in exploring region homogeneity, intensity inhomogeneity, and boundary-defining features. The learning capacity of STM-RENet is further enhanced by developing a new CB-STM-RENet that exploits channel boosting and learns textural variations to effectively screen the X-ray images of COVID-19 infection. The idea of channel boosting is exploited by generating auxiliary channels from the two additional CNNs using Transfer Learning, which are then concatenated to the original channels of the proposed STM-RENet. A significant performance improvement is shown by the proposed CB-STM-RENet in comparison to the standard CNNs on three datasets, especially on the stringent CoV-NonCoV-15k dataset. The good detection rate (97%), accuracy (96.53%), and reasonable F-score (95%) of the proposed technique suggest that it can be adapted to detect COVID-19 infected patients.

4.
Comput Biol Med ; 137: 104816, 2021 10.
Article in English | MEDLINE | ID: covidwho-1372942

ABSTRACT

The new emerging COVID-19, declared a pandemic disease, has affected millions of human lives and caused a massive burden on healthcare centers. Therefore, a quick, accurate, and low-cost computer-based tool is required to timely detect and treat COVID-19 patients. In this work, two new deep learning frameworks: Deep Hybrid Learning (DHL) and Deep Boosted Hybrid Learning (DBHL), is proposed for effective COVID-19 detection in X-ray dataset. In the proposed DHL framework, the representation learning ability of the two developed COVID-RENet-1 & 2 models is exploited individually through a machine learning (ML) classifier. In COVID-RENet models, Region and Edge-based operations are carefully applied to learn region homogeneity and extract boundaries features. While in the case of the proposed DBHL framework, COVID-RENet-1 & 2 are fine-tuned using transfer learning on the chest X-rays. Furthermore, deep feature spaces are generated from the penultimate layers of the two models and then concatenated to get a single enriched boosted feature space. A conventional ML classifier exploits the enriched feature space to achieve better COVID-19 detection performance. The proposed COVID-19 detection frameworks are evaluated on radiologist's authenticated chest X-ray data, and their performance is compared with the well-established CNNs. It is observed through experiments that the proposed DBHL framework, which merges the two-deep CNN feature spaces, yields good performance (accuracy: 98.53%, sensitivity: 0.99, F-score: 0.98, and precision: 0.98). Furthermore, a web-based interface is developed, which takes only 5-10s to detect COVID-19 in each unseen chest X-ray image. This web-predictor is expected to help early diagnosis, save precious lives, and thus positively impact society.


Subject(s)
COVID-19 , Humans , SARS-CoV-2 , X-Rays
5.
Photodiagnosis Photodyn Ther ; 35: 102473, 2021 Sep.
Article in English | MEDLINE | ID: covidwho-1331143

ABSTRACT

BACKGROUND: The recent emergence of a highly infectious and contagious respiratory viral disease known as COVID-19 has vastly impacted human lives and overloaded the health care system. Therefore, it is crucial to develop a fast and accurate diagnostic system for the timely identification of COVID-19 infected patients and thus to help control its spread. METHODS: This work proposes a new deep CNN based technique for COVID-19 classification in X-ray images. In this regard, two novel custom CNN architectures, namely COVID-RENet-1 and COVID-RENet-2, are developed for COVID-19 specific pneumonia analysis. The proposed technique systematically employs Region and Edge-based operations along with convolution operations. The advantage of the proposed idea is validated by performing series of experimentation and comparing results with two baseline CNNs that exploited either a single type of pooling operation or strided convolution down the architecture. Additionally, the discrimination capacity of the proposed technique is assessed by benchmarking it against the state-of-the-art CNNs on radiologist's authenticated chest X-ray dataset. Implementation is available at https://github.com/PRLAB21/Coronavirus-Disease-Analysis-using-Chest-X-Ray-Images. RESULTS: The proposed classification technique shows good generalization as compared to existing CNNs by achieving promising MCC (0.96), F-score (0.98) and Accuracy (98%). This suggests that the idea of synergistically using Region and Edge-based operations aid in better exploiting the region homogeneity, textural variations, and region boundary-related information in an image, which helps to capture the pneumonia specific pattern. CONCLUSIONS: The encouraging results of the proposed classification technique on the test set with high sensitivity (0.98) and precision (0.98) suggest the effectiveness of the proposed technique. Thus, it suggests the potential use of the proposed technique in other X-ray imagery-based infectious disease analysis.


Subject(s)
COVID-19 , Deep Learning , Photochemotherapy , Algorithms , Humans , Neural Networks, Computer , Photochemotherapy/methods , Photosensitizing Agents , Radiography, Thoracic , SARS-CoV-2 , X-Rays
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